Alnylam Pharmaceuticals, Inc. vs Marathon Petroleum Corp — how do they compare? Alnylam Pharmaceuticals, Inc. trades at $223.95 (market cap $29.60B), while Marathon Petroleum Corp trades at $343.99 (market cap $94.48B). The key difference: Marathon Petroleum Corp is far larger — about 3.2× Alnylam Pharmaceuticals, Inc.'s market cap, and Marathon Petroleum Corp pays a 1.19% dividend while Alnylam Pharmaceuticals, Inc. pays none. Which is the better fit depends on your goals.
| ALNY | MPC | |
|---|---|---|
Market Cap | $29.60B | $94.48B |
Sector | Health | Energy |
52-Week High | $491.22 | $336.42 |
52-Week Low | $205.48 | $159.11 |
Enterprise Value | $27.56B | $121.00B |
Dividend Yield | — | 1.19% |
Signals from Pluang's Aura AI — not financial advice
ALNY trades at $222.54, up 2.56% today, amid a bearish technical signal with support at $218 and resistance at $223. The company reported strong revenue growth to $3.71B in 2025 and turned profitable with net income of $313.75M, though recent Q2 2026 earnings missed estimates. Analyst consensus remains bullish with a $370.07 price target, but multiple law firms are investigating potential securities fraud, creating near-term uncertainty.
The outlook is mixed: robust fundamentals and analyst support suggest long-term upside, but legal risks and recent earnings volatility pose significant headwinds. Investors face tension between strong profitability metrics and heightened sentiment risks from ongoing investigations.
Marathon Petroleum (MPC) trades at $342.47, up 6.91% with strong technical momentum and bullish analyst sentiment. The stock demonstrates robust fundamentals with Q2 2026 EPS of $17.73 beating estimates by 22.1%, supported by refining margin strength and disciplined operations. Valuation metrics remain attractive with P/E of 11.67 and EV/EBITDA of 6.87, while maintaining strong profitability with 47.9% ROE.
MPC presents a compelling investment case with projected revenue growth to $153.6B in 2026 and net profit margin expansion to 5.56%. Key risks include refining margin volatility and geopolitical impacts on energy markets. With 25 buy ratings and no sell recommendations, Wall Street consensus targets $332.70, though current price exceeds this level by 2.9%.
Trailing returns across standard periods
Latest headlines on both assets
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia.
Read more on ALNY →Marathon Petroleum is an independent refiner with 13 refineries in the midcontinent, West Coast, and Gulf Coast of the United States with total throughput capacity of 2.9 million barrels per day. Its Dickinson, ND, facility produces 184 million gallons a year of renewable diesel. Its Martinez, CA, facility will have the ability to produce 730 million gallons a year of renewable diesel once converted. The firm also owns and operates midstream assets primarily through its listed MLP, MPLX.
Read more on MPC →