Alnylam Pharmaceuticals, Inc. vs VanEck Gold Miners ETF — how do they compare? Alnylam Pharmaceuticals, Inc. trades at $224 (market cap $29.60B), while VanEck Gold Miners ETF trades at $90.84. The key difference: VanEck Gold Miners ETF is trading nearer its 52-week high, Alnylam Pharmaceuticals, Inc. nearer its low. Which is the better fit depends on your goals.
| ALNY | GDX | |
|---|---|---|
Market Cap | $29.60B | — |
Sector | Health | — |
52-Week High | $491.22 | $115.84 |
52-Week Low | $205.48 | $56.60 |
Enterprise Value | $27.56B | — |
Signals from Pluang's Aura AI — not financial advice
ALNY trades at $223.43, up 2.97% in 24 hours, with a bearish technical signal despite recent gains. The stock shows strong profitability with a 79.65% gross margin and 96.55% ROE, but valuation ratios like P/E of 38.54 are elevated. Recent Q2 2026 earnings missed estimates, and multiple law firms are investigating potential securities fraud, adding uncertainty.
Outlook is mixed: analyst consensus is bullish with a $370.07 price target, but risks include ongoing fraud probes and earnings volatility. Revenue growth is robust, projected to reach $4.8B in 2026, yet investors face headwinds from legal issues and technical bearishness.
GDX (VanEck Gold Miners ETF) trades at $90.96, up 0.52% with a bullish technical signal from moving averages but overbought RSI readings. The ETF benefits from gold's seven-week rally to near $4,300/oz, though mining stocks have lagged the metal's gains. Recent institutional activity shows mixed sentiment with City Holding reducing its position by 85.8% while Axiom Investment added a $934,000 stake in Q1 2026.
Gold miners offer leveraged exposure to rising gold prices with attractive valuations, but face volatility risks. The sector's free cash flow yields are at record highs, supporting potential upside if gold sustains momentum. Key risks include gold price sensitivity, mining operational challenges, and competition from physical gold ETFs with lower expense ratios.
Trailing returns across standard periods
Latest headlines on both assets
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia.
Read more on ALNY →The fund normally invests at least 80% of its total assets in common stocks and depositary receipts of companies involved in the gold mining industry. The index is a modified market-capitalization weighted index primarily comprised of publicly traded companies involved in the mining for gold and silver. The fund is non-diversified.
Read more on GDX →