Alnylam Pharmaceuticals, Inc. vs EPAM Systems Inc — how do they compare? Alnylam Pharmaceuticals, Inc. trades at $221.2 (market cap $29.60B), while EPAM Systems Inc trades at $99.88 (market cap $5.15B). The key difference: Alnylam Pharmaceuticals, Inc. is far larger — about 5.7× EPAM Systems Inc's market cap, and EPAM Systems Inc is trading nearer its 52-week high, Alnylam Pharmaceuticals, Inc. nearer its low. Which is the better fit depends on your goals.
| ALNY | EPAM | |
|---|---|---|
Market Cap | $29.60B | $5.15B |
Sector | Health | Technology |
52-Week High | $491.22 | $221.40 |
52-Week Low | $205.48 | $76.04 |
Enterprise Value | $27.56B | $4.52B |
Signals from Pluang's Aura AI — not financial advice
ALNY trades at $223.43, up 2.97% in 24 hours, with a bearish technical signal despite recent gains. The stock shows strong profitability with a 79.65% gross margin and 96.55% ROE, but valuation ratios like P/E of 38.54 are elevated. Recent Q2 2026 earnings missed estimates, and multiple law firms are investigating potential securities fraud, adding uncertainty.
Outlook is mixed: analyst consensus is bullish with a $370.07 price target, but risks include ongoing fraud probes and earnings volatility. Revenue growth is robust, projected to reach $4.8B in 2026, yet investors face headwinds from legal issues and technical bearishness.
EPAM Systems trades at $100.29, up 3.0% with recent earnings beats but faces technical bearish signals. The company reported strong Q2 2026 results with EPS of $3.38 beating estimates, though revenue guidance was lowered due to North American softness. Valuation appears attractive with P/E of 13.55 and P/S of 0.97, while profitability metrics remain solid with 7.15% net margin.
The stock presents a value opportunity with analyst consensus target of $117.27 (17% upside), but faces near-term headwinds from reduced revenue guidance and technical weakness. Key risks include slowing demand in core markets, while the OpenAI partnership offers AI growth potential. Institutional sentiment remains positive with 65% buy ratings.
Trailing returns across standard periods
Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway within cells for sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia.
Read more on ALNY →EPAM Systems Inc provides software product development and digital platform engineering services to clients located around the world. The company services include Software Product Development, Custom Application Development, Application Testing, Enterprise Application Platforms, Application Maintenance, and Support and Infrastructure Management. The company focuses on innovative and scalable software solutions. The company uses industry standard and custom developed technology, tools, and platforms to deliver results to handle business challenges. The company primarily offers its solutions in the following industries: financial services, travel and consumer, software and hi-tech, life sciences and healthcare. The majority of revenue is generated from North American clients.
Read more on EPAM →