Price movement over the last 24 hours
Enact Holdings Inc vs Vertex Pharmaceuticals Incorporated — how do they compare? Enact Holdings Inc trades at $45.17 (market cap $6.35B), while Vertex Pharmaceuticals Incorporated trades at $510.34 (market cap $132.55B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 20.9× Enact Holdings Inc's market cap, and Enact Holdings Inc pays a 1.91% dividend while Vertex Pharmaceuticals Incorporated pays none. Which is the better fit depends on your goals.
| ACT | VRTX | |
|---|---|---|
Market Cap | $6.35B | $132.55B |
Sector | Technology | Health |
52-Week High | $45.71 | $529.59 |
52-Week Low | $34.39 | $366.54 |
Enterprise Value | $6.55B | $127.29B |
Dividend Yield | 1.91% | — |
Signals from Pluang's Aura AI — not financial advice
ACT trades at $45.69, up 0.77% today, with a bullish technical signal and strong moving averages. The stock shows robust fundamentals with a net income margin of 54.49% and a P/E ratio of 9.89. Recent news includes a 14% dividend increase announced on May 5, 2026, and Q1 2026 earnings that met expectations. Analyst consensus is a $47.50 price target with a mix of buy and hold ratings.
Outlook remains positive due to high profitability and dividend growth, but risks include earnings volatility and market sensitivity. Upside is supported by institutional sentiment and consistent cash flow, though investors should monitor execution against future earnings estimates.
Vertex Pharmaceuticals (VRTX) trades at $522.25, down 1.1% on the day but remains near its all-time high. The stock shows strong fundamentals with 35.5% net income margins and robust cash flow generation. Recent developments include a $10 billion acquisition of Crinetics Pharmaceuticals and FDA approval for expanded use of its gene therapy CASGEVY in younger patients. Technical indicators show bullish moving averages but overbought oscillators with RSI readings above 89.
The outlook remains positive with 84% analyst buy ratings and a consensus price target of $522. Key catalysts include the Crinetics acquisition's $5 billion peak sales potential and continued gene therapy expansion. Risks include integration challenges from the major acquisition and potential regulatory hurdles. The stock trades at premium valuations (P/E 31.4) but justifies this with strong profitability and growth prospects.
Trailing returns across standard periods
Latest headlines on both assets
Enact Holdings is a leading private mortgage insurance provider in the U.S. It partners with lenders to offer credit enhancement and risk management solutions, helping more borrowers achieve and maintain homeownership.
Read more on ACT →Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →