American Airlines Group Inc vs Vertex Pharmaceuticals Incorporated — how do they compare? American Airlines Group Inc trades at $15.35 (market cap $10.55B), while Vertex Pharmaceuticals Incorporated trades at $528 (market cap $134.25B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 12.7× American Airlines Group Inc's market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, American Airlines Group Inc nearer its low. Which is the better fit depends on your goals.
| AAL | VRTX | |
|---|---|---|
Market Cap | $10.55B | $134.25B |
Sector | Industrials | Health |
52-Week High | $18.15 | $529.65 |
52-Week Low | $10.18 | $376.62 |
Enterprise Value | $38.51B | $128.37B |
Trailing returns across standard periods
American Airlines is the world's largest airline by scheduled revenue passenger miles. The firm's major hubs are Charlotte, Chicago, Dallas/Fort Worth, Los Angeles, Miami, New York, Philadelphia, Phoenix, and Washington, D.C. After completing a major fleet renewal, the company has the youngest fleet of U.S. legacy carriers.
Read more on AAL →Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →