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Zentalis reports promising Phase 1b trial results for azenosertib plus paclitaxel in resistant ovarian cancer.

Company Fundamentals
21 May 2026
GlobeNewsWire
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Bullish
pluang ai news

Zentalis Pharmaceuticals announced encouraging Phase 1b trial data showing that combining their investigational drug azenosertib with paclitaxel achieved a 39% overall response rate and a median progression-free survival of 7.3 months in patients with platinum-resistant ovarian cancer. The combination demonstrated manageable safety with low rates of severe side effects, especially at the 250 mg intermittent dose, which showed a 50% response rate and durable responses. These results suggest azenosertib could enhance treatment options for ovarian cancer, supporting further clinical development and broader testing in other cancers where taxanes are used. Data were presented at the 2026 ASCO meeting, with additional combination data forthcoming.

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