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Whitehawk advances MUC16-targeted ADC for ovarian and endometrial cancers, with Phase 1 data expected in 2027

Market News
10 Apr 2026
PRNewsWire
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Bullish
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Whitehawk Therapeutics presented data showing MUC16 is highly expressed in ovarian and aggressive endometrial cancers, supporting their ADC drug HWK-016 targeting this protein. MUC16's stable, high expression across cancer stages and subtypes makes it a promising target. HWK-016, designed to target the membrane-bound portion of MUC16, is in Phase 1 trials for advanced ovarian and endometrial cancers, with initial clinical data expected in the first half of 2027. This development could improve treatment options for these difficult-to-treat cancers.

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