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Phase 3 trial shows telitacicept cuts proteinuria by 55% in IgA nephropathy, preserving kidney function.

Company Fundamentals
14 May 2026
GlobeNewsWire
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Bullish
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Vor Bio announced that the Phase 3 TELIGAN trial of telitacicept in IgA nephropathy patients in China showed a 55% relative reduction in proteinuria compared to placebo after 39 weeks, with kidney function (eGFR) remaining stable. The trial results, published in The New England Journal of Medicine, highlight telitacicept's potential as a dual BAFF/APRIL therapy for autoimmune diseases. The drug also reduced the risk of significant kidney function decline and showed consistent benefits across patient subgroups. Vor Bio is advancing telitacicept in global trials for other autoimmune diseases, aiming for broader regulatory approvals.

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