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Single infusion of VERVE-102 cuts LDL cholesterol up to 62%, showing promise for heart disease treatment.

Company Fundamentals
25 May 2026
PRNewsWire
View Source
Bullish
pluang ai news

Eli Lilly's Phase 1b Heart-2 trial showed that a single intravenous dose of VERVE-102 significantly lowered PCSK9 protein and LDL cholesterol (LDL-C) in patients at high risk for cardiovascular disease, with reductions lasting up to 18 months. The treatment mimics natural genetic variants that protect against heart disease by turning off the PCSK9 gene in the liver. VERVE-102 was well tolerated with no serious side effects, and Lilly plans to start Phase 2 trials by the end of 2026. This new gene editing approach could transform heart disease management from chronic medication to a one-time treatment.

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