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Spyre Therapeutics completes enrollment in SKYWAY trial for SPY072 in rheumatic diseases, with key data expected in late 2026.

Market News
03 Jun 2026
GlobeNewsWire
View Source
Bullish
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Spyre Therapeutics has completed enrollment for all sub-studies in its SKYWAY Phase 2 trial evaluating SPY072, an anti-TL1A antibody, in rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA). This milestone highlights strong patient interest and the urgent need for new treatments in these conditions affecting over three million U.S. patients. Spyre expects topline data readouts for RA in Q3 2026 and for PsA and axSpA in Q4 2026. The company aims to deliver six Phase 2 trial results in 2026, potentially setting a new standard in rheumatic disease treatment with SPY072’s extended half-life and convenient dosing schedule.

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