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Over 75% of tough-to-control Type 2 diabetes patients show elevated cortisol linked to heart risks, says Sparrow Pharma.

Company Fundamentals
15 Jun 2026
Globe News Wire
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Bullish
pluang ai news

Sparrow Pharmaceuticals revealed interim data from its Phase 2b CAPTAIN-T2D trial showing that over 75% of patients with difficult-to-control Type 2 diabetes have elevated cortisol levels, which are associated with higher cardiovascular disease risk. The study found that inadequate glycemic control and hypertension correlated with higher cortisol. The drug clofutriben, an oral HSD-1 inhibitor, is being tested to reduce cortisol and improve metabolic health. These findings highlight cortisol's role in treatment resistance and the potential of targeting it to improve outcomes in Type 2 diabetes patients.

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