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Sitryx completes enrollment in Phase 1b trial of oral SYX-5219 for atopic dermatitis, data expected Q4 2026

Company Fundamentals
22 Jun 2026
Na
View Source
Bullish
pluang ai news

Sitryx Therapeutics has completed enrollment ahead of schedule in its Phase 1b trial of SYX-5219, a first-in-class oral PKM2 modulator, targeting moderate to severe atopic dermatitis. The randomized, placebo-controlled study involves 50 adults across the US and Europe and aims to evaluate safety, tolerability, and initial efficacy. This milestone highlights strong patient and clinician interest in a novel oral treatment that could offer durable disease remission by modulating immune function rather than just managing symptoms. Data from the trial is expected in the fourth quarter of 2026, following promising Phase 1a results showing safety and immune modulation.

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