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Silexion gets Israeli approval to start Phase 2/3 trial of SIL204 for pancreatic cancer, trial begins Q2 2026.

Company Fundamentals
18 May 2026
GlobeNewsWire
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Bullish
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Silexion Therapeutics received approval from the Israeli Ministry of Health to initiate its Phase 2/3 clinical trial of SIL204, a novel RNA interference therapy targeting KRAS-driven pancreatic cancer. The company also submitted a clinical trial application in Germany, aiming to start the trial in Q2 2026 across multiple EU sites and Israel. This trial will evaluate SIL204 combined with chemotherapy in patients with locally advanced pancreatic cancer, addressing a critical need for new treatments. Financially, Silexion reported increased R&D and administrative expenses due to trial preparations and raised capital to support ongoing development and Nasdaq compliance.

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