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First patient dosed in Phase 1b trial of Sapu003, an IV everolimus for advanced mTOR-sensitive tumors

Market News
13 May 2026
Sapu Nano / Oncotelic Therapeutics
View Source
Bullish
pluang ai news

Sapu Nano and Oncotelic have dosed the first patient in a Phase 1b clinical trial of Sapu003, an intravenous formulation of everolimus designed to treat advanced mTOR-sensitive solid tumors such as HR+/HER2- breast cancer and renal cell carcinoma. This trial aims to evaluate safety, tolerability, and preliminary anti-tumor effects with weekly IV dosing. The new formulation seeks to improve drug exposure and reduce side effects compared to oral everolimus. The study's progress marks a key step toward expanding treatment options for cancers with mTOR pathway involvement.

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