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RYBREVANT plus LAZCLUZE shows nearly 3.5 years median survival in tough EGFR-mutated lung cancer cases.

Company Fundamentals
29 May 2026
PRNewsWire
View Source
Bullish
pluang ai news

Johnson & Johnson announced that their drug combination RYBREVANT (amivantamab-vmjw) plus LAZCLUZE (lazertinib) achieved a median overall survival of nearly 3.5 years in patients with advanced non-small cell lung cancer (NSCLC) harboring atypical EGFR mutations. This result, presented at ASCO 2026, marks a significant improvement over current treatments, which typically offer less than two years of survival. The combination targets multiple disease drivers and showed consistent responses across mutation subgroups, including those with historically poor outcomes. These findings reinforce the potential of RYBREVANT-based regimens as a durable first-line treatment option for this difficult-to-treat cancer subtype.

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