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AstraZeneca's tozorakimab shows third phase III success, eyeing up to $5bn sales potential in COPD treatment

Market News
21 Apr 2026
Proactive Investors
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Bullish
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AstraZeneca's tozorakimab achieved a third positive phase III trial result in treating chronic obstructive pulmonary disease (COPD), reinforcing its potential as a blockbuster drug. The MIRANDA trial demonstrated significant reductions in moderate-to-severe exacerbations across various patient groups, supporting Citi's $3.5 billion peak sales estimate, with potential upside from current smokers and high eosinophil patients. AstraZeneca projects peak sales between $3 billion and $5 billion, indicating room for growth beyond Citi's base case. Analysts noted a slight change in the trial announcement's tone but remain optimistic ahead of full data release.

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