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FDA approves Utebzi, first oral carbapenem for complicated UTIs, boosting Spero Therapeutics' growth potential.

Market News
18 Jun 2026
Seeking Alpha
View Source
Bullish
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Spero Therapeutics and partner GSK received FDA approval for Utebzi, the first oral carbapenem treatment for complicated urinary tract infections. This approval positions Spero to earn milestone payments and royalties from GSK, with potential annual revenues around $50 million and further upside if Utebzi becomes a blockbuster drug. Despite recent stock volatility and a limited drug pipeline, Spero's low cash burn and funding runway through 2028 support a positive outlook for risk-tolerant investors. Analyst Edmund Ingham initiates coverage with a Buy rating, viewing the stock as undervalued relative to its future revenue potential but notes the investment carries high risk and uneven returns.

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