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Iadademstat shows strong safety and efficacy in AML trials, with 100% response in first-line treatment.

Company Fundamentals
13 May 2026
GlobeNewsWire
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Bullish
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Oryzon Genomics announced updated positive clinical data for iadademstat, an LSD1 inhibitor, in acute myeloid leukemia (AML) from two Phase Ib trials. In first-line AML treatment combined with azacitidine and venetoclax, iadademstat demonstrated a 100% overall response rate and a 93% composite complete remission rate, with a favorable safety profile and an estimated 12-month overall survival of 74%. In relapsed/refractory FLT3-mutated AML, iadademstat combined with gilteritinib showed a 67% composite complete remission rate and good safety. These results support accelerated clinical development plans and will be presented at the European Hematology Association Congress in June 2026.

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Greenlight hits Ohio license cap with 4 new dispensaries and adds manufacturing operations.

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Comcast faces price target cuts amid rising competition and NBCUniversal spin-off plans

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