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Higher dose Wegovy leads to nearly 28% weight loss in early responders after 72 weeks, preserving muscle health.

Company Fundamentals
12 May 2026
GlobeNewsWire
View Source
Bullish
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Novo Nordisk's STEP UP trial shows that the higher 7.2 mg dose of Wegovy (semaglutide) enables early responders to lose an average of 27.7% body weight after 72 weeks, significantly more than the 2.4 mg dose or placebo. Most weight loss came from fat reduction (84%), with muscle mass largely preserved and muscle function improved. These findings highlight Wegovy's effectiveness and safety in treating obesity, offering hope for better long-term weight management. Novo Nordisk presented these results at the 2026 European Congress on Obesity and plans further publication.

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