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Eli Lilly's obesity drug retatrutide sets new weight-loss record, challenging Novo Nordisk's market lead.

Market News
22 May 2026
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Eli Lilly's experimental obesity drug retatrutide achieved a 28% body weight loss over 80 weeks in a pivotal phase III trial, surpassing Novo Nordisk's leading treatments Wegovy and Ozempic. While retatrutide shows higher efficacy, it also has a higher discontinuation rate due to adverse effects, including gastrointestinal issues and skin sensations. Detailed data will be presented at the American Diabetes Association conference in June. This development poses a significant competitive threat to Novo Nordisk's dominant position in the obesity drug market.

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