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NextCure's SIM0505 shows 55% response in tough gynecologic cancers in Phase 1 trial

Company Fundamentals
01 Jun 2026
GlobeNewsWire
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Bullish
pluang ai news

NextCure and Simcere Zaiming presented positive Phase 1 data for SIM0505, an antibody drug conjugate targeting CDH6, showing a 55% objective response rate in heavily pretreated gynecologic cancer patients, including 52.9% in ovarian cancer and 66.7% in uterine serous carcinoma. The drug demonstrated favorable safety and tolerability, supporting ongoing dose optimization focused on platinum-resistant ovarian cancer. These results highlight SIM0505's potential as a new treatment option for difficult-to-treat gynecologic cancers, with plans for further pivotal studies.

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Lotto.com appoints new COO and VP of HR to drive US digital lottery expansion

Lotto.com appoints new COO and VP of HR to drive US digital lottery expansion

Lotto.com has appointed Ruxandra Tereanu as Chief Operating Officer and Amanda Coyle as Vice President of Human Resources to strengthen its leadership team amid ongoing expansion in the US digital lottery market. Tereanu brings 13 years of experience...

Company Fundamentals
Bullish
16 minutes ago
Worldline schedules H1 2026 results call for July 30, with webcast and Q&A for analysts.

Worldline schedules H1 2026 results call for July 30, with webcast and Q&A for analysts.

Worldline has announced a conference call to discuss its H1 2026 financial results on July 30, 2026, at 6:30 pm CET. The event will be accessible via webcast, and sell-side analysts can participate in a Q&A session by pre-registering. The press relea...

Company Fundamentals
Neutral
16 minutes ago
Ipsen repurchases 28,541 shares in early July at an average price of €166.05 per share.

Ipsen repurchases 28,541 shares in early July at an average price of €166.05 per share.

Ipsen Pharma conducted a share buy-back program from July 6 to July 10, 2026, repurchasing a total of 28,541 shares. The average purchase price during this period was €166.05 per share. This buy-back activity reflects Ipsen's strategy to manage its c...

Company Fundamentals
Neutral
16 minutes ago
Ipsen Pharma repurchases 28,541 shares at an average price of €166 in early July 2026

Ipsen Pharma repurchases 28,541 shares at an average price of €166 in early July 2026

Ipsen Pharma conducted share buybacks from July 6 to July 10, 2026, purchasing a total of 28,541 shares. The average purchase price was €166.05 per share. These buybacks were made under Article 5 of the MAR regulation, indicating a structured repurch...

Company Fundamentals
Neutral
16 minutes ago
Barclays raises Hudbay Minerals price target to $32 on strong copper growth outlook.

Barclays raises Hudbay Minerals price target to $32 on strong copper growth outlook.

Barclays increased its price target for Hudbay Minerals to $32 from $30, citing strong growth prospects in copper mining. Despite a recent nearly 30% stock pullback due to market sentiment, Hudbay maintains a solid financial position with near-zero n...

Analyst Insights
Bullish
1 hour ago
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