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Navacaprant fails Phase 3 trials; Neumora halts its development, focusing on other drug candidates.

Company Fundamentals
15 Jun 2026
Na
View Source
Bearish
pluang ai news

Neumora Therapeutics announced that its Phase 3 KOASTAL-2 and -3 trials for navacaprant, a treatment for major depressive disorder, did not meet primary or key secondary endpoints, leading to discontinuation of navacaprant's development. Despite this setback, the company remains focused on advancing other promising programs targeting Alzheimer's agitation, schizophrenia, and cardiometabolic disease, with several clinical milestones expected by the end of 2026. Neumora is also reducing its workforce by 35% to save costs and has a cash runway extending into the third quarter of 2027.

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