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Phase 2 study shows ALXN1840 significantly improves copper balance in Wilson disease patients.

Company Fundamentals
19 May 2026
GlobeNewsWire
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Bullish
pluang ai news

Monopar Therapeutics announced that a Phase 2 study published in Hepatology Communications demonstrated ALXN1840 (tiomolibdate choline) significantly improves copper balance in patients with Wilson disease by increasing fecal copper excretion. The open-label trial involved nine patients and showed rapid, sustained copper mobilization, even in those with long-term prior treatment. ALXN1840 was well tolerated with no serious adverse events, reinforcing its potential as a new treatment option for this rare genetic disorder. These findings support ongoing development and regulatory efforts for ALXN1840.

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