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MetaVia starts dosing higher DA-1726 doses in Phase 1 trial for obesity treatment.

Others
10 Apr 2026
PRNewsWire
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Bullish
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MetaVia Inc. has begun dosing the first patient in Part 3 of its Phase 1 trial for DA-1726, a novel dual GLP-1/glucagon receptor agonist aimed at treating obesity. This phase tests one-step and two-step dose titrations to safely reach higher doses (48 mg and 64 mg) over 16 weeks, aiming to improve weight loss and tolerability compared to current therapies. Early results showed about 9% weight loss at 48 mg with positive effects on waist size and blood sugar control. Data from this trial are expected by Q4 2026, which could support DA-1726 as a more effective and easier-to-dose obesity treatment.

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