Mastercard now supports 24/7 stablecoin settlement with USDC, PYUSD, RLUSD on eight blockchains.

Mastercard has launched support for on-chain settlement using regulated stablecoins including USDC, PYUSD, and RLUSD across eight blockchain networks such as Ethereum and Solana. This new system enables 24/7 settlement, including intraday windows, weekends, and public holidays, addressing liquidity timing gaps in traditional payment systems. Early partners like Cross River, Lead Bank, and Nuvei are already live, with initial rollout in the US and Latin America and plans for global expansion through 2026. The move aims to enhance real-world utility of stablecoins by integrating them into mainstream payment infrastructure with existing security and fraud protections.