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Zenkuda shows strong efficacy and safety in Phase 3 GLOW2 study for diabetic retinopathy with 6-month dosing.

Company Fundamentals
26 Mar 2026
PRNewsWire
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Bullish
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Kodiak Sciences announced positive Phase 3 GLOW2 trial results for Zenkuda (tarcocimab tedromer), an anti-VEGF biologic for diabetic retinopathy. Zenkuda demonstrated significant superiority over sham treatment, with 62.5% of patients achieving a ≥2-step improvement in diabetic retinopathy severity and an 85% reduction in sight-threatening complications, all on a 6-month dosing schedule. The treatment was well tolerated with no intraocular inflammation and low cataract rates. These results support Kodiak's plan to accelerate the biologics license application (BLA) submission for Zenkuda, which also shows promise across multiple retinal diseases and in patients using GLP-1 medications, reflecting real-world use.

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