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New study shows DecisionDx-Melanoma test better predicts melanoma lymph node risk than MIA nomogram

Market News
25 Jun 2026
PRNewsWire
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Bullish
pluang ai news

A new prospective multicenter study published in Dermatology and Therapy finds that Castle Biosciences' DecisionDx-Melanoma i31-SLNB test more accurately identifies patients at low and high risk of sentinel lymph node (SLN) positivity in cutaneous melanoma than the Melanoma Institute Australia (MIA) nomogram. The i31-SLNB test showed a 2.6% SLN positivity rate for low-risk patients, below the 5% threshold for avoiding biopsy, compared to 5.8% for the MIA nomogram, which failed to identify patients below this threshold. This improved accuracy supports better clinical decision-making on whether to perform sentinel lymph node biopsy, potentially reducing unnecessary surgeries and complications. The study reinforces the value of integrating tumor biology with clinical factors for personalized melanoma care.

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Global automotive microcontrollers market to reach $34.31B by 2035, driven by ADAS, electrification, and software-defined vehicles.

Global automotive microcontrollers market to reach $34.31B by 2035, driven by ADAS, electrification, and software-defined vehicles.

The global automotive microcontrollers market is projected to grow from USD 15.49 billion in 2025 to USD 34.31 billion by 2035, at a CAGR of 8.28%. Growth is fueled by increasing adoption of advanced driver-assistance systems (ADAS), vehicle electrif...

Market News
Bullish
3 hours ago
Alpaca raises $435M to expand into prime brokerage amid AI-driven trading surge

Alpaca raises $435M to expand into prime brokerage amid AI-driven trading surge

Alpaca, a brokerage infrastructure startup, secured $435 million in funding to enter prime brokerage services, challenging traditional Wall Street firms. The company’s API supports 94% of US equities and powers tokenized stocks for Kraken. Alpaca’s t...

Market News
Bullish
4 hours ago
Raymond James Financial upgraded to Buy on strong Q3 outlook and growth in key segments

Raymond James Financial upgraded to Buy on strong Q3 outlook and growth in key segments

Raymond James Financial's rating was raised to "Buy" after positive investor event disclosures and a promising preview of its upcoming quarterly results. The company is expected to exceed earnings per share consensus for Q3 FY26, driven by strong per...

Analyst Insights
Bullish
4 hours ago
Bitcoin and Ethereum see $59M outflows as traders shift to stablecoins amid market caution.

Bitcoin and Ethereum see $59M outflows as traders shift to stablecoins amid market caution.

Bitcoin and Ethereum experienced combined outflows exceeding $59 million as traders moved funds into stablecoins like USDT and fiat currencies, signaling a cautious stance in the crypto market. This rotation reflects a short-term defensive strategy, ...

Market News
Bearish
4 hours ago
Whales accumulate 70M XRP as network adoption grows, signaling confidence despite price consolidation below resistance.

Whales accumulate 70M XRP as network adoption grows, signaling confidence despite price consolidation below resistance.

Whales have accumulated 70 million XRP over the past week, showing strong confidence despite XRP's price consolidating below resistance levels. The XRP Ledger surpassed 8 million activated accounts, indicating growing network adoption across payments...

Market News
Bullish
4 hours ago
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