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Kali Therapeutics licenses KT501 tri-specific antibody to Sanofi for $180M upfront, targeting autoimmune diseases.

Company Fundamentals
23 Mar 2026
PRNewsWire
View Source
Bullish
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Kali Therapeutics has entered a licensing deal with Sanofi, granting exclusive global rights to KT501, a tri-specific T-cell engager aimed at treating B cell-mediated autoimmune diseases. Sanofi will pay $180 million upfront and could pay up to $1.05 billion in milestones plus royalties. KT501 is currently in early human trials for Rheumatoid Arthritis, designed to deplete B cells effectively while minimizing side effects. This collaboration leverages Kali's innovative protein engineering to potentially offer safer, more effective autoimmune treatments.

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