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Johnson & Johnson's IMAAVY shows strong results for rare blood disorder wAIHA in Phase 2/3 trial

Company Fundamentals
11 Jun 2026
Vandana Singh
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Bullish
pluang ai news

Johnson & Johnson announced that its drug IMAAVY (nipocalimab-aahu) achieved a significant and durable hemoglobin response in patients with warm autoimmune hemolytic anemia (wAIHA) during a Phase 2/3 trial. Patients receiving the 30 mg/kg dose showed rapid improvement, with nearly two-thirds achieving key hemoglobin targets by Week 24, along with reduced fatigue and steroid use. The drug works by blocking the neonatal Fc receptor to reduce harmful antibodies while preserving immune function. These positive results support the FDA's Priority Review of IMAAVY's supplemental Biologics License Application, potentially advancing treatment options for this rare disorder.

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