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Jade Biosciences doses first patient in Phase 2 trial of JADE101 for IgA nephropathy, data expected in 2027

Market News
26 May 2026
GlobeNewsWire
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Bullish
pluang ai news

Jade Biosciences has dosed the first participant in its Phase 2 JUNIPER trial testing JADE101, a monoclonal antibody targeting APRIL, for treating IgA nephropathy, a chronic autoimmune kidney disease. JADE101 aims to reduce pathogenic IgA production, potentially slowing disease progression and preserving kidney function. The trial will assess safety, efficacy, and kidney function markers in about 30 patients, with interim data expected in 2027. This development is significant as IgA nephropathy often requires lifelong treatment and can lead to kidney failure.

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