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Intellia's CRISPR therapy lonvo-z shows strong Phase 3 results, cutting hereditary angioedema attacks by 87%.

Company Fundamentals
13 Jun 2026
GlobeNewsWire
View Source
Bullish
pluang ai news

Intellia Therapeutics announced positive Phase 3 trial results for lonvoguran ziclumeran (lonvo-z), a CRISPR-based one-time treatment for hereditary angioedema (HAE). The trial showed an 87% reduction in monthly HAE attacks compared to placebo, with 62% of patients attack-free over six months. The treatment also improved patients' quality of life and demonstrated a favorable safety profile. Intellia is advancing lonvo-z toward FDA approval, expecting a U.S. launch in the first half of 2027.

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