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Inhibikase launches global Phase 3 trial for PAH drug IKT-001, reports $48.3M net loss in 2025

Company Fundamentals
26 Mar 2026
GlobeNewsWire
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Bullish
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Inhibikase Therapeutics initiated a global pivotal Phase 3 clinical trial called IMPROVE-PAH for its drug IKT-001 targeting Pulmonary Arterial Hypertension (PAH), following FDA approval and site activations in the US. The adaptive trial will enroll around 486 patients worldwide with endpoints measuring pulmonary vascular resistance and walking distance. The company raised $115 million in a public offering in 2025 and ended the year with $178.8 million in cash. Despite a net loss of $48.3 million in 2025, Inhibikase is advancing regulatory approvals in over 20 countries and aims to accelerate trial timelines through the EU's FAST-EU initiative.

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