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Phase 3 trial shows 70% complete response in low-grade UTUC with Padeliporfin VTP treatment

Company Fundamentals
16 May 2026
Impact Biotech
View Source
Bullish
pluang ai news

ImPact Biotech announced updated Phase 3 ENLIGHTED trial results showing 70% complete response in patients with low-grade upper tract urothelial carcinoma (UTUC) treated with Padeliporfin VTP. The treatment demonstrated durable effects, with 85.7% of patients maintaining complete response for at least 12 months, and a median response duration of nearly 24 months. The therapy was well-tolerated with mostly mild side effects. ImPact plans regulatory submission in 2027 and is exploring commercialization opportunities, highlighting Padeliporfin VTP as a promising minimally invasive option for UTUC patients.

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