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IDEAYA and Roche team up to test cancer drugs IDE892 and RG6505 in pancreatic cancer patients with MTAP deletion.

Market News
03 Jun 2026
PRNewsWire
View Source
Bullish
pluang ai news

IDEAYA Biosciences has partnered with Roche to conduct a clinical trial combining IDE892, a PRMT5 inhibitor, with Roche's RG6505, a pan-RAS inhibitor, targeting pancreatic ductal adenocarcinoma (PDAC) patients who have MTAP deletion and RAS mutations. IDEAYA will sponsor the trial while Roche supplies RG6505, with joint oversight from both companies. This collaboration aims to address the high unmet need in PDAC, where up to 40% of tumors show MTAP deletion, potentially improving treatment outcomes for patients lacking targeted options. Future plans include exploring a triple combination therapy involving IDE397, another IDEAYA drug.

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