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Apalutamide plus hormone therapy cuts prostate cancer metastasis risk by 20% in Phase 3 PROTEUS study

Company Fundamentals
31 May 2026
PRNewsWire
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Bullish
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Johnson & Johnson's Phase 3 PROTEUS study found that combining apalutamide with hormone therapy before and after prostate cancer surgery significantly improves outcomes for high-risk localized or locally advanced prostate cancer patients. The treatment made patients nine times more likely to have minimal or no cancer at surgery and reduced the risk of metastasis or death by 20%. It also extended the time before additional therapy was needed to over six years. These results, presented at ASCO 2026 and published in The New England Journal of Medicine, suggest a new approach beyond surgery alone to improve long-term survival.

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