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Fulcrum Therapeutics shares plunge 49.7% after halting sickle cell drug development.

Market News
02 Jun 2026
Tanya Rawat
View Source
Bearish
pluang ai news

Fulcrum Therapeutics' stock dropped nearly 50% in after-hours trading after the company announced it is discontinuing its lead experimental drug, pociredir, for sickle cell disease. The decision follows FDA concerns about cancer risks linked to the drug's target pathway, leaving no regulatory path forward. Fulcrum is now conducting a strategic review, considering options like mergers or acquisitions, while cutting costs to preserve capital. The company holds $333.3 million in cash and securities as it evaluates its future direction.

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