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Citi stays neutral on GSK despite breakthrough hepatitis B drug due to commercial uncertainties.

Market News
29 May 2026
Proactive Investors
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Neutral
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Citi maintains a neutral rating on GSK shares despite promising clinical trial results for its hepatitis B drug, bepirovirsen, which showed a functional cure in up to 26% of patients. The cautious stance is due to unresolved commercial issues such as drug pricing, initial market access, and the practicality of required monitoring in real-world settings. Bepirovirsen offers a new treatment approach by silencing the virus's replication instructions, potentially improving on current therapies that rarely cure the disease. Hepatitis B affects around 300 million people globally, and Citi forecasts peak annual sales of £1.6 billion for the drug, aligning with market expectations.

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