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Galmed's Aramchol boosts prostate cancer drug Xtandi's effectiveness in preclinical study, promising better treatment.

Market News
17 Aug 2026
PRNewsWire
View Source
Bullish
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Galmed Pharmaceuticals announced preclinical results showing that combining Aramchol with Xtandi (enzalutamide) increased prostate cancer cell death by 3-4 times compared to Xtandi alone. Xtandi, a major prostate cancer drug with global sales of $8 billion in 2024, faces patent expirations in 2026-2027 and upcoming U.S. price cuts. The combination targets lipid metabolism pathways linked to drug resistance, potentially improving treatment for resistant or advanced prostate cancer. Galmed plans to pursue partnerships based on a new patent application for this combination therapy, aiming to extend Xtandi's lifecycle and differentiate it from generics.

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