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All 12 Type 1 diabetes patients in trial achieved insulin independence with tegoprubart-based islet transplant.

Company Fundamentals
08 Jun 2026
GlobeNewsWire
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Bullish
pluang ai news

Eledon Pharmaceuticals announced that all 12 patients with Type 1 diabetes in a University of Chicago trial achieved insulin independence after receiving islet cell transplants combined with tegoprubart, an anti-CD40L antibody. Patients showed improved blood sugar control with average HbA1c dropping to 5.4%, and no severe hypoglycemia occurred post-transplant. The tegoprubart regimen avoided common toxicities linked to standard immunosuppressants, showing promise as a safer alternative. The company plans to seek FDA guidance to advance tegoprubart toward market approval for islet transplantation.

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