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Pemvidutide shows significant liver fibrosis improvement in MASH patients after 24 weeks in Phase 2b trial

Market News
27 May 2026
GlobeNewsWire
View Source
Bullish
pluang ai news

Altimmune's Phase 2b trial data reveal that pemvidutide, a dual glucagon/GLP-1 receptor agonist, significantly improves multiple non-invasive markers of metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis after 24 weeks. AI-based digital pathology confirmed notable fibrosis regression, with up to 68.6% of patients showing improvement versus placebo. These results highlight pemvidutide's potential to treat MASH by addressing liver fat, inflammation, and fibrosis simultaneously. Based on these promising findings, Altimmune plans to start a Phase 3 trial later in 2026 to further evaluate pemvidutide's efficacy.

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