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Celosia Therapeutics starts Phase 1b trial of CTx1000 targeting ALS protein TDP-43.

Others
23 Mar 2026
PRNewsWire
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Bullish
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Celosia Therapeutics has begun dosing the first participant in its Phase 1b KOANEWA trial to test CTx1000, a genetic medicine aimed at clearing pathological TDP-43 protein in ALS patients. This trial, conducted at Macquarie University Hospital, focuses on safety and tolerability while exploring potential efficacy in modifying ALS progression. CTx1000 is based on a discovery identifying a binder to TDP-43, which in preclinical models halted and partially reversed ALS symptoms. This marks a significant step toward a potential new treatment for this fatal neurodegenerative disease.

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Telo Genomics reports positive interim results for blood test predicting relapse risk in multiple myeloma patients.

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Meta alerts parents if teens discuss self-harm with its AI chatbot, plans emergency contact feature.

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