Study shows optical genome mapping outperforms traditional methods in multiple myeloma analysis

Bionano Genomics announced a study published in the American Journal of Hematology demonstrating that optical genome mapping (OGM) significantly outperforms traditional methods like karyotyping, FISH, and next-generation sequencing in detecting chromosomal abnormalities in multiple myeloma. The study, involving 211 samples, showed OGM had higher success rates, identified additional pathogenic abnormalities missed by other methods, and resolved cases where traditional methods failed. This advancement could improve genomic profiling in multiple myeloma, aligning with recommendations from major medical societies and potentially driving wider adoption of OGM technology.