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BioAge starts Phase 2 trial of BGE-102, a novel oral drug to reduce cardiovascular risk by targeting inflammation

Market News
16 Jun 2026
GlobeNewsWire
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Bullish
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BioAge Labs has dosed the first participant in its Phase 2 QUELL-CV trial testing BGE-102, a new oral NLRP3 inhibitor aimed at reducing cardiovascular risk by lowering systemic inflammation. The randomized, placebo-controlled study will evaluate three doses over 12 weeks in about 160 adults with obesity and elevated inflammation. The primary goal is to measure changes in hsCRP, a key inflammation marker linked to heart disease. Positive Phase 1 results showed strong hsCRP reductions and good tolerance, and topline Phase 2 data are expected in late 2026. This trial will guide dose selection for Phase 3 and supports further development of BGE-102 for cardiovascular and retinal diseases.

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