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aTyr Pharma advances efzofitimod Phase 3 trial for pulmonary sarcoidosis with FDA feedback

Market News
11 May 2026
GlobeNewsWire
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Bullish
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aTyr Pharma announced plans to continue developing efzofitimod for pulmonary sarcoidosis after a positive FDA Type C meeting. The company will submit an IND in June 2026 for a new global Phase 3 trial focusing on patients with chronic, symptomatic pulmonary sarcoidosis and restrictive lung disease. The trial will use forced vital capacity (FVC) as the primary endpoint and the King's Sarcoidosis Questionnaire (KSQ-Lung) as a key secondary endpoint, reflecting FDA guidance. The study aims to enroll about 372 patients and increase dosing frequency to enhance efficacy while maintaining safety. This development offers hope for improved treatment options in a disease with limited therapies.

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