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Amplia Therapeutics partners with Lilly for lung cancer drug trial combining narmafotinib and olomorasib

Market News
04 Aug 2026
Proactive Investors - Finance
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Bullish
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Amplia Therapeutics has entered a clinical collaboration with Eli Lilly to test their drug narmafotinib combined with Lilly's KRAS G12C inhibitor olomorasib in advanced non-small cell lung cancer (NSCLC) patients. The Phase 1b/2b trial will evaluate safety and efficacy as a second-line treatment for KRAS G12C-mutated NSCLC, starting late 2026 in Australia and the US. This expands narmafotinib's use beyond pancreatic and ovarian cancers, targeting resistance mechanisms to improve treatment outcomes. The collaboration taps into a lung cancer market valued at $31 billion, expected to grow significantly by 2033.

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