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Amplia and ANZGOG launch trial of narmafotinib with chemo for ovarian cancer patients unresponsive to platinum therapy

Company Fundamentals
08 May 2026
GlobeNewsWire
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Bullish
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Amplia Therapeutics and the Australia New Zealand Gynaecological Oncology Group (ANZGOG) have partnered to conduct a clinical trial testing narmafotinib combined with standard chemotherapy in ovarian cancer patients who do not respond to platinum-based treatment. The PRROSE trial will enroll 15-20 patients with high-grade serous ovarian cancer to evaluate safety and potential improvement in surgical outcomes. This study addresses a critical need as about 20% of ovarian cancer patients fail initial chemotherapy, limiting surgery options and worsening prognosis. Biomarker analysis will also explore narmafotinib's mechanism to support future treatment development.

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