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Allogene's cema-cel shows promise in early CAR T therapy for high-risk LBCL with strong safety and efficacy data.

Analyst Insights
13 Apr 2026
Seeking Alpha
View Source
Bullish
pluang ai news

Allogene Therapeutics is advancing cema-cel, a CAR T therapy targeting earlier intervention in high-risk large B-cell lymphoma (LBCL). Interim ALPHA3 trial data revealed 58.3% minimal residual disease (MRD) negativity for cema-cel versus 16.7% in observation, highlighting its potential effectiveness and a favorable safety profile suitable for outpatient use. Despite a recent stock rally, the market undervalues Allogene's platform, with an enterprise value under $500 million. The analyst maintains a long-term buy rating, anticipating future event-free survival (EFS) results to confirm cema-cel's best-in-class potential, though short-term volatility is expected.

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