Investment
Features
FeesSafety
Academy
More
Pluang+

ALN1003 shows promising preclinical effects on insulin resistance and liver health in obesity models

Market News
18 May 2026
GlobeNewsWire
View Source
Bullish
pluang ai news

Alaunos Therapeutics reported preclinical data from diet-induced obesity mouse studies showing that ALN1003, their oral metabolic drug candidate, improved insulin-resistance biomarkers, adipose tissue signaling, and liver histology related to metabolic syndrome. The drug lowered fasting insulin and HOMA-IR scores, increased beneficial adiponectin levels, and reduced liver fat accumulation in treated animals. These findings suggest ALN1003 may target multiple aspects of metabolic syndrome, including obesity, insulin resistance, and liver disease, supporting further preclinical development. The company plans additional studies to optimize dosing and better understand mechanisms, while noting the data are early and from non-GLP studies with limited sample sizes.

More News

AngioDynamics jumps on strong Q4 sales and raised price target to $19 by H.C. Wainwright

AngioDynamics jumps on strong Q4 sales and raised price target to $19 by H.C. Wainwright

AngioDynamics reported an 8% revenue increase to $86.6 million in Q4, driven by a 16.7% sales rise in its Med Tech division, notably from NanoKnife and AlphaVac products. H.C. Wainwright raised the price target from $16 to $19 and maintained a Buy ra...

Company Fundamentals
Bullish
37 minutes ago
PNC beats Q2 earnings estimates with record revenue, but shares fall on expense and deposit concerns.

PNC beats Q2 earnings estimates with record revenue, but shares fall on expense and deposit concerns.

PNC Financial Services Group reported Q2 2026 adjusted EPS of $4.85 and record revenue of $6.88 billion, surpassing analyst expectations. The growth was driven by a 15.5% rise in net interest income and a 31.4% increase in fee income, reflecting stro...

Company Fundamentals
Neutral
45 minutes ago
Greenlight hits Ohio license cap with 4 new dispensaries and adds manufacturing operations.

Greenlight hits Ohio license cap with 4 new dispensaries and adds manufacturing operations.

Greenlight, a leading cannabis operator, expanded its Ohio presence by opening four new dispensaries and adding in-state manufacturing, reaching the state's maximum allowed eight dispensaries. This move strengthens Greenlight's position in Ohio's lim...

Company Fundamentals
Bullish
1 hour ago
Halper Sadeh LLC probes fairness of deals for ESI, CRNX, SOLS shareholders amid merger sales.

Halper Sadeh LLC probes fairness of deals for ESI, CRNX, SOLS shareholders amid merger sales.

Halper Sadeh LLC is investigating whether shareholders of Element Solutions Inc (ESI), Crinetics Pharmaceuticals (CRNX), and Solstice Advanced Materials (SOLS) are receiving fair treatment in their respective sale and merger transactions. The firm hi...

Market News
Bearish
1 hour ago
Comcast faces price target cuts amid rising competition and NBCUniversal spin-off plans

Comcast faces price target cuts amid rising competition and NBCUniversal spin-off plans

Investment banks Scotiabank and Bernstein have lowered their price targets for Comcast due to increased competition from new players like SpaceX's Starlink and valuation risks. Comcast is also undergoing a major strategic shift by spinning off its NB...

Analyst Insights
Bearish
1 hour ago
banner-footerbanner-footer

Invest & Trade with
#1 Award-Winning Investment Super App