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Aclaris reports positive Phase 1a trial results for ATI-052 antibody and advances ATI-2138 for lichen planus treatment

Market News
28 Apr 2026
GlobeNewsWire
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Bullish
pluang ai news

Aclaris Therapeutics announced positive full results from its Phase 1a trial of ATI-052, a novel anti-TSLP/IL-4Rα bispecific antibody showing strong potency, safety, and a long half-life enabling up to three-month dosing. The company is progressing ATI-052 into Phase 1b trials for asthma and atopic dermatitis, with Phase 2b planned for late 2026. Additionally, Aclaris selected lichen planus as the lead indication for ATI-2138, an oral ITK/JAK3 inhibitor targeting pathogenic T cells, with a Phase 2b basket study expected to start in the second half of 2026. These developments highlight Aclaris' focus on innovative treatments for immuno-inflammatory diseases with significant unmet needs.

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