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European Commission approves expanded VENCLYXTO combos for untreated chronic lymphocytic leukemia (CLL)

Market News
29 May 2026
PRNewsWire
View Source
Bullish
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The European Commission has authorized expanded use of VENCLYXTO (venetoclax) in combination with acalabrutinib (with or without obinutuzumab) and with ibrutinib for treating adults with previously untreated chronic lymphocytic leukemia (CLL). Supported by Phase 3 AMPLIFY, GLOW, and Phase 2 CAPTIVATE trials, these all-oral, fixed-duration regimens offer effective, chemotherapy-free options that may allow patients treatment-free intervals. This approval extends across the EU, Iceland, Norway, and Liechtenstein, providing more targeted first-line therapies that improve progression-free survival and quality of life for CLL patients.

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